Case Studies
Phase III Reducing Venous Thromboembolism Risk study
- 14 out of 20 sites in Macedonia decided to hire IRN for a study coordinator services provider
- 6 Site coordinators allocated for the sites on a regional principle – one Site Coordinator covers 2 to 3 nearby sites with careful planning of the on-site visits depending on the study schedule and recruitment rates
- Median recruitment in IRN supported sites is 227% better than the global average and 23, 40% better than the country average
Phase III COPD study
- 2 sites from IRN Site Alliance Network initiated for the study
- Due to overload of the site staff both of the sites did not start recruitment after study initiation
- IRN hired by the sites for a study coordinator services
- 2 Site Coordinators assigned for each site during the study conduct
- At the study end average recruitment in the world was 7, 54 pts/ site, in Bulgaria – 10, 6 pts/site and in IRN supported sites – 15, 5 pts/site
- Median recruitment was 105% better than the global average and 46% better than the country average
Phase III Hospital Acquired Pneumonia Study
- Largest 5 Intensive Care Units in Bulgaria initiated in Q1 2016
- No patients screened or randomized till the end of Q3 2017
- IRN hired by the Sponsor as study coordinator and patient recruitment and retention service provider
- Based on careful analysis of the patient specifics, our Site Alliance Specialists approached different departments within the institutions and in other hospitals (sites from our Alliance network) as referrals
- 22 patients pre-screened by our staff, 9 of them were screened and 6 enrolled for 3 months
- 3 of the sites approached IRN to extend their site management services for other studies as well
Phase III Infectious diseases study
- 1 IRN site participating in Bulgaria
- 50 patients enrolled in 3 weeks upon initiation
Home care
- 138 home care nurses recruited in less than a month in Bulgaria
- 2 country leads managed nurses for 17 sites
- Including the home care nurses to the site teams improved the patients’ compliance and decreased the sites’ burden significantly.