Case studies

Phase III Reducing Venous Thromboembolism Risk study

14 out of 20 sites in Macedonia decided to hire IRN for a study coordinator services provider
6 Site coordinators allocated for the sites on a regional principle – one Site Coordinator covers 2 to 3 nearby sites with careful planning of the on-site visits depending on the study schedule and recruitment rates
Median recruitment in IRN supported sites is 227% better than the global average and 23, 40% better than the country average

Phase III COPD study

2 sites from IRN Site Alliance Network initiated for the study
Due to overload of the site staff both of the sites did not start recruitment after study initiation
IRN hired by the sites for a study coordinator services
2 Site Coordinators assigned for each site during the study conduct
At the study end average recruitment in the world was 7, 54 pts/ site, in Bulgaria – 10, 6 pts/site and in IRN supported sites – 15, 5 pts/site
Median recruitment was 105% better than the global average and 46% better than the country average

Phase III Hospital Acquired Pneumonia Study

Largest 5 Intensive Care Units in Bulgaria initiated in Q1 2016
No patients screened or randomized till the end of Q3 2017
IRN hired by the Sponsor as study coordinator and patient recruitment and retention service provider
Based on careful analysis of the patient specifics, our Site Alliance Specialists approached different departments within the institutions and in other hospitals (sites from our Alliance network) as referrals
22 patients pre-screened by our staff, 9 of them were screened and 6 enrolled for 3 months
3 of the sites approached IRN to extend their site management services for other studies as well

Phase III Infectious diseases study

Home care

138 home care nurses recruited in less than a month in Bulgaria
2 country leads managed nurses for 17 sites
Including the home care nurses to the site teams improved the patients’ compliance and decreased the sites’ burden significantly.